Week 1: September 14, 16
Lecture 1: Protein Structure I – JJ Miranda
Lecture 2: Working With and Purifying Proteins – Jonathan Weissman
Week 2: September 21, 23
Lecture 3: Determining and Analyzing Molecular Interactions – Geeta Narlikar
Lecture 4: Diffusion and Brownian Motion (notes) , (slides) – Dyche Mullins
Week 3: September 28, 30
Lecture 5: Pre-steady State Kinetics (slides) – Dyche Mullins
Lecture 6: Kinetics Workshop – Dyche Mullins
Problem Set 1 due Friday, October 2 by 5 pm
Week 4: October 5, 7
Lecture 7: Thermodynamics I – Geeta Narlikar
Lecture 8: Thermodynamics II – Geeta Narlikar
** TA Kinetics Workshop: Wednesday 2 - 4 pm GH S201
Week 5: October 12, 14
Lecture 9: Binding and Cooperativity I – Geeta Narlikar
Lecture 10: *CANCELLED* Binding and Cooperativity II – Geeta Narlikar
** TA Thermo Workshop: Wednesday 2 - 4 pm GH S201
Problem Set 2 due Friday, October 16 by 5 pm
Week 6: October 19, 21
Lecture 11: Enzyme Kinetics – Geeta Narlikar
Lecture 12: Enzyme Workshop – Geeta Narlikar
Week 7: October 26, 28
Lecture 13: Mass Spectrometry – Jonathan Weissman
Lecture 14: Protein Structure II – JJ Miranda
Problem Set 3 due Friday, October 30 by 5 pm
Week 8: November 2, 4
Lecture 15: X-Ray Crystallography I - Dave Agard
Lecture 16: X-Ray Crystallography II - Dave Agard (same file as above)
Week 9: November 9, 11
Lecture 17: Cryo-Electron Microscopy – Yifan Cheng
Lecture 18: NMR Spectroscopy – John Gross
** TA Course Review: Wednesday 2 - 4 pm GH S201
Week 10: November 16, 18
Lecture 19: System Biology – Jonathan Weissman
Lecture 20: Statistics and Data Analysis – Jonathan Weissman (same file as Lecture 13)
Week 11: November 23
Lecture 21: Fluorescence Spectroscopy – Dyche Mullins
(Thanksgiving Holiday)
Problem Set 4 due Monday, November 23 by 5pm
Week 12: November 30, December 2
Lecture 22: Single Molecule Techniques – Dyche Mullins
Lecture 23: TBA
Final Exam: To be handed out November 23. Due Friday, December 11.
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